Anesthesia Sensitivity – Redheads Have It
By Kara Wilkins
While redheads may be blessed in the hue department, they do have to deal with something that blonds and brunettes avoid just by being born with their hair color. Research has shown that people with red hair need larger doses of pain medication when they go to the dentist. And that makes them more nervous about dental procedures, according to research published in The Journal of the American Dental Association. Redheads are more sensitive to pain because of a mutation in a gene that affects hair color, researchers say. In people with brown, black and blond hair, the gene, for the melanocortin-1 receptor, produces melanin. But a mutation in the MC1R gene results in the production of a substance called pheomelanin that results in red hair and fair skin. The MC1R gene belongs to a family of receptors that include pain receptors in the brain, and as a result, a mutation in the gene appears to influence the body’s sensitivity to pain. A 2004 study showed that redheads require, on average, about 20 percent more general anesthesia than people with dark hair or blond coloring. And in 2005, researchers found that redheads are more resistant to the effects of local anesthesia, such as the numbing drugs used by dentists. So if you are a redhead, don’t be afraid to go to the dentist. Just talk to your dentist about the possibility that you might need a little more pain medication than other patients. And be proud of your hair!
While redheads may be blessed in the hue department, they do have to deal with something that blonds and brunettes avoid just by being born with their hair color. Research has shown that people with red hair need larger doses of pain medication when they go to the dentist. And that makes them more nervous about dental procedures, according to research published in The Journal of the American Dental Association. Redheads are more sensitive to pain because of a mutation in a gene that affects hair color, researchers say. In people with brown, black and blond hair, the gene, for the melanocortin-1 receptor, produces melanin. But a mutation in the MC1R gene results in the production of a substance called pheomelanin that results in red hair and fair skin. The MC1R gene belongs to a family of receptors that include pain receptors in the brain, and as a result, a mutation in the gene appears to influence the body’s sensitivity to pain. A 2004 study showed that redheads require, on average, about 20 percent more general anesthesia than people with dark hair or blond coloring. And in 2005, researchers found that redheads are more resistant to the effects of local anesthesia, such as the numbing drugs used by dentists. So if you are a redhead, don’t be afraid to go to the dentist. Just talk to your dentist about the possibility that you might need a little more pain medication than other patients. And be proud of your hair!